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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: AFNHSDLDAE LRRLFRERYR LHPKFVAAVH YEQPTIQIEL RQNTSQKAAG EVDIGDAAYY FERDIKGESL
Highest antigen sequence indentity to the following orthologs: Rat - 81%, Mouse - 81%.
TROP2 is a carcinoma-associated antigen defined by the monoclonal antibody GA733. This antigen is a member of a family including at least two type I membrane proteins. It transduces an intracellular calcium signal and acts as a cell surface receptor. Mutations of its gene result in gelatinous drop-like corneal dystrophy, an autosomal recessive disorder characterized by severe corneal amyloidosis leading to blindness.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cell surface glycoprotein Trop-2; GA733; Membrane component chromosome 1 surface marker 1; Pancreatic carcinoma marker protein GA733-1; TACD2; Tumor-associated calcium signal transducer 2
Gene Aliases: GA733-1; M1S1; TACSTD2; TROP2
Entrez Gene ID: (Human) 4070
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