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Invitrogen
SESTD1 Polyclonal Antibody
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Product Details
PA5-84370
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human SESTD1. Recombinant protein control fragment (Product #RP-105965).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: PQVMKLLDSL REQYTRYQEV CRQRSKRTQL EEIQQKVMQV VNWLEGPGSE QLRAQWGIGD SIRASQALQQ KHEEIESQHS EWFAVYVEL
Highest antigen sequence indentity to the following orthologs: Rat - 100%, Mouse - 100%.
Target Information
SESTD1 was initially identified in mutant zebrafish with defects in the spontaneous contraction and touch response as a novel gene, solo, encoding a protein containing SEC14 and spectrin repeat domains. Other experiments indicated that SESTD1 interacts with the TRPC4 and TRPC5, members of the transient receptor potential channel family, via the TRPC calmodulin- and inositol 1, 4, 5-triphosphate receptor-binding domain and is essential for efficient receptor-mediated activation of TRPC5, suggesting that SESTD1 is a novel regulator of these TRPC proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Huntingtin-interacting protein-like protein; Protein Solo; SEC14 and spectrin domains 1; SEC14 domain and spectrin repeat-containing protein 1
Gene Aliases: SESTD1; SOLO
UniProt ID: (Human) Q86VW0
Entrez Gene ID: (Human) 91404
phosphatidylserine binding
protein binding
1-phosphatidylinositol binding
phosphatidylinositol-4,5-bisphosphate binding
phosphatidylinositol-5-phosphate binding
phosphatidylcholine binding
phosphatidylinositol-3-phosphate binding
phosphatidylinositol-3,4-bisphosphate binding
phosphatidylinositol-4-phosphate binding
phosphatidic acid binding
phosphatidylinositol-3,5-bisphosphate binding
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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