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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: SQPTMTQTSS SQGGLGGLSL TTEPVSSNPG YIPSSEANRP SHLSSTGT
Highest antigen sequence indentity to the following orthologs: Rat - 37%, Mouse - 40%.
The protein encoded by this gene is primarily found in endothelial cells and blood vessels, where it is involved in cell shape changes and EGF-induced cell migration. It can enhance the activation of vascular endothelial growth factor receptor-2/kinase insert domain receptor and also promote the proteolysis of internalized kinase insert domain receptor. This gene may play a role in angiogenesis-related diseases. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: apoptosis regulator through modulating IAP expression; apoptosis regulator through modulating IAPs expression; endothelial cell-specific molecule 2
Gene Aliases: ARIA; ECSM2
UniProt ID: (Human) Q19T08
Entrez Gene ID: (Human) 641700
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