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Invitrogen
PLCH2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-84908
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human PLCH2. Recombinant protein control fragment (Product #RP-108606).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: AEEDVESGED AGASRRNGRL VVGSFSRRKK KGSKLKKAAS VEEGDEGQDS PGGQSRGATR QKKTMKLSR
Highest antigen sequence indentity to the following orthologs: Mouse - 75%, Rat - 80%.
Target Information
PLCH2 is a member of the PLC-eta family of the phosphoinositide-specific phospholipase C (PLC) superfamily of enzymes that cleave PtdIns(4,5) P2 to generate second messengers inositol 1,4,5-trisphosphate and diacylglycerol (Zhou et al., 2005 [PubMed 16107206]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: enzyme; phosphoinositide phospholipase C-eta-2; phosphoinositide phospholipase C-like 4; phospholipase C-eta2; phospholipase C-like 4; phospholipase C-like protein 4
Gene Aliases: PLC-eta2; PLC-L4; PLCeta2; PLCL4
UniProt ID: (Human) O75038
Entrez Gene ID: (Human) 9651
lipid metabolic process
signal transduction
phospholipase C-activating G-protein coupled receptor signaling pathway
intracellular signal transduction
phosphatidylinositol metabolic process
phosphatidylinositol-mediated signaling
release of sequestered calcium ion into cytosol
positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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