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Invitrogen
ARID1B Polyclonal Antibody
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Product Details
PA5-84983
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human ARID1B. Recombinant protein control fragment (Product #RP-108041).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: HEGDMYNMQY SSQQQEMYNQ YGGSYSGPDR RPIQGQYPYP YSRERMQGPG QIQTHGIPPQ MMG
Highest antigen sequence indentity to the following orthologs: Rat - 94%, Mouse - 94%.
Target Information
This locus encodes an AT-rich DNA interacting domain-containing protein. The encoded protein is a component of the SWI/SNF chromatin remodeling complex and may play a role in cell-cycle activation. The protein encoded by this locus is similar to AT-rich interactive domain-containing protein 1A. These two proteins function as alternative, mutually exclusive ARID-subunits of the SWI/SNF complex. The associated complexes play opposing roles. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Feb 2012].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ARID domain-containing protein 1B; AT rich interactive domain 1B (SWI1-like); AT-rich interactive domain-containing protein 1B; BAF250B; BRG1-associated factor 250b; BRG1-binding protein ELD/OSA1; BRG1-binding protein hELD/OSA1; chromatin remodelling factor; DAN15; ELD (eyelid)/OSA protein; hOsa2; Osa homolog 2; p250R; unnamed protein product
Gene Aliases: 6A3-5; ARID1B; BAF250B; BRIGHT; CSS1; DAN15; ELD/OSA1; KIAA1235; MRD12; OSA2; P250R; SMARCF2
UniProt ID: (Human) Q8NFD5
Entrez Gene ID: (Human) 57492
chromatin organization
chromatin remodeling
regulation of transcription from RNA polymerase II promoter
nervous system development
regulation of mitotic metaphase/anaphase transition
positive regulation of T cell differentiation
positive regulation of cell differentiation
positive regulation of myoblast differentiation
positive regulation of gene expression, epigenetic
positive regulation of transcription, DNA-templated
regulation of G0 to G1 transition
regulation of G1/S transition of mitotic cell cycle
positive regulation of double-strand break repair
regulation of nucleotide-excision repair
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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