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Invitrogen
CD109 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-100711
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human CD109(Accession Q6YHK3), corresponding to amino acid residues S1397-L1445.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total CD109.
Target Information
CD109 is a member of the alpha2-macroglobulin/complement superfamily. The encoded GPI-linked glycoprotein is found on the cell surface of platelets, activated T-cells, and endothelial cells. The protein binds to and negatively regulates signaling of transforming growth factor beta (TGF-beta).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 150 kDa TGF-beta-1-binding protein; activated T-cell marker CD109; AMCOM; alpha2-macroglobulin/complement; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7; GARP; Gov platelet alloantigens; GPI-anchored alpha 2 macroglobulin-related protein; GPI-anchored membrane protein; human platelet antigen 15; platelet-specific Gov antigen; RP11-525G3.1; unnamed protein product
Gene Aliases: 9930012E15Rik; CPAMD7; GARP; HPA-15; p180; r150
UniProt ID: (Human) Q6YHK3, (Mouse) Q8R422
Entrez Gene ID: (Human) 135228, (Mouse) 235505
negative regulation of protein phosphorylation
hair follicle development
negative regulation of keratinocyte proliferation
negative regulation of transforming growth factor beta receptor signaling pathway
regulation of keratinocyte differentiation
negative regulation of wound healing
osteoclast fusion
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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