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Invitrogen
CC2D1A Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-100876
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human CC2D1A(Accession Q6P1N0), corresponding to amino acid residues P668-I718.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total CC2D1A.
Target Information
This gene encodes a transcriptional repressor that binds to a conserved 14-bp 5'-repressor element and regulates expression of the 5-hydroxytryptamine (serotonin) receptor 1A gene in neuronal cells. The DNA binding and transcriptional repressor activities of the protein are inhibited by calcium. A mutation in this gene results in nonsyndromic mental retardation-3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 5-HT1A receptor; Akt kinase-interacting protein 1; five prime repressor element under dual repression-binding protein 1; five repressor element under dual repression-binding protein 1; five' repressor element under dual repression binding protein 1; FLJ20241; FRE under dual repression-binding protein 1; freud-1; lethal (2) giant discs homolog 2; putative NF-kappa-B-activating protein 023N; putative NFkB activating protein; repressor of serotonin-1A receptor; TBK1-associated protein in endolysosomes; unnamed protein product
Gene Aliases: Aki-1; FREUD-1; Freud-1/Aki1; Lgd2; MRT3; RGD1306108; TAPE
UniProt ID: (Human) Q6P1N0, (Mouse) Q8K1A6, (Rat) Q66HA5
Entrez Gene ID: (Human) 54862, (Mouse) 212139, (Rat) 288908
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
protein binding
cadherin binding
regulation of transcription from RNA polymerase II promoter
positive regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of snRNA transcription by RNA polymerase II
negative regulation of transcription from RNA polymerase II promoter
regulation of respiratory gaseous exchange by neurological system process
endosome organization
regulation of respiratory gaseous exchange
dendrite arborization
apical dendrite arborization
regulation of postsynapse assembly
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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