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Invitrogen
PNPLA8 Polyclonal Antibody
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FIGURE: 1 / 5
PNPLA8 Antibody (PA5-101477) in IHC (P)
Immunohistochemistry analysis of PNPLA8 in human colorectal cancer. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with PNPLA8 polyclonal antibody (Product # PA5-101477) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-101477
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human PNPLA8(Accession Q9NP80), corresponding to amino acid residues L697-K747.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total PNPLA8.
Target Information
Phospholipase A2 catalyzes cleavage of fatty acids from phospholipids, thereby regulating membrane physical properties and the release of lipid second messengers and growth factors. Phospholipase A2 activity also modulates cellular growth programs, inflammation, and ion channel function (Mancuso et al., 2000 [PubMed 10744668]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: intracellular membrane-associated calcium-independent phospholipase A2 gamma; iPLA2 gamma; iPLA2-gamma; membrane-associated calcium-independent phospholipase A2 gamma; patatin like phospholipase domain containing 8; patatin-like phospholipase domain containing 8; patatin-like phospholipase domain-containing protein 8; unnamed protein product
Gene Aliases: 1200006O19Rik; Ipla2(gamma); IPLA2-2; IPLA2G; iPLA2gamma; MMLA; PNPLA-gamma; RGD1311444
UniProt ID: (Human) Q9NP80, (Rat) D3ZRC4, (Mouse) Q8K1N1
Entrez Gene ID: (Human) 50640, (Rat) 314075, (Mouse) 67452
prostaglandin biosynthetic process
lipid metabolic process
fatty acid metabolic process
arachidonic acid metabolic process
cardiolipin metabolic process
phosphatidylcholine catabolic process
intracellular signal transduction
linoleic acid metabolic process
phosphatidylethanolamine catabolic process
arachidonic acid secretion
lipid homeostasis
triglyceride homeostasis
regulation of cellular response to oxidative stress
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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