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Invitrogen
IL11RA Polyclonal Antibody
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FIGURE: 1 / 4
IL11RA Antibody (PA5-102002) in IHC (P)
Immunohistochemistry analysis of IL11RA in mouse brain tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with IL11RA polyclonal antibody (Product # PA5-102002) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-102002
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human IL11RA(Accession Q14626), corresponding to amino acid residues W327-F377.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total IL11RA.
Target Information
Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. This gene encodes the IL-11 receptor, which is a member of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2012].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: enhancer trap locus homolog 2; etl-2; IL-11 receptor subunit alpha; IL-11 receptor subunit alpha-1; IL-11R subunit alpha; IL-11R subunit alpha-1; IL-11R-alpha; IL-11R-alpha-1; IL-11RA; Il-11ra-alpha; IL-11RA1; interleukin 11 receptor, alpha; interleukin 11 receptor, alpha chain 1; interleukin 11 receptor, alpha chain 2; interleukin-11 receptor alpha chain; locus 2; novel cytokine receptor 1; NR-1; sIL11RA; unnamed protein product
Gene Aliases: CRSDA; GP130; Il-11ra; Il11ra; Il11ra2; NR1
UniProt ID: (Human) Q14626, (Rat) Q99MF4, (Mouse) Q64385
Entrez Gene ID: (Human) 3590, (Rat) 245983, (Mouse) 16157
natural killer cell differentiation
placenta development
female pregnancy
embryo implantation
positive regulation of cell proliferation
cytokine-mediated signaling pathway
developmental process
interleukin-11-mediated signaling pathway
decidualization
maternal process involved in female pregnancy
head development
negative regulation of cytokine-mediated signaling pathway
B cell differentiation
megakaryocyte differentiation
positive regulation of MAPK cascade
negative regulation of cytokine activity
cell differentiation
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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