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Invitrogen
ANT Polyclonal Antibody
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FIGURE: 1 / 3
ANT Antibody (PA5-102508) in IHC (P)
Immunohistochemistry analysis of ANT in mouse kidney tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with ANT polyclonal antibody (Product # PA5-102508) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-102508
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Bovine
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human SLC25A4(Accession P12235), corresponding to amino acid residues V78-L128.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total SLC25A4.
Target Information
ANT1 catalyzes the exchange of ADP and ATP across the mitochondrial inner membrane.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: adenine nucleotide translocase-1; adenine nucleotide translocator 1; adenine nucleotide translocator 1 (skeletal muscle); adenine nucleotide translocator 1, skeletal muscle; adenine nucleotide translocator), member 4; ADP ATP translocase; ADP,ATP carrier protein 1; ADP,ATP carrier protein, heart/skeletal muscle; ADP.ATP translocase; ADP/ADT translocator protein; ADP/ATP carrier 1; ANT 1; heart/skeletal muscle ATP/ADP translocator; mitochondrial adenine nucleotide translocator; progressive external ophthalmoplegia 2; progressive external ophthalmoplegia 3; solute carrier family 25 (mitochondrial adenine nucleotide translocator) member 4; solute carrier family 25 (mitochondrial carrier; solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator) member 4 isoform SLC25A4_1; solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator) member 4 isoform SLC25A4_2; solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator) member 4 isoform SLC25A4_3; solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4; solute carrier family 25 member 4; unnamed protein product
Gene Aliases: AAC1; ANT; ANT 1; ANT1; mANC1; MTDPS12; MTDPS12A; PEO2; PEO3; PEOA2; T1
UniProt ID: (Human) P12235, (Mouse) P48962, (Rat) Q05962
Entrez Gene ID: (Human) 291, (Mouse) 11739, (Rat) 85333
apoptotic mitochondrial changes
negative regulation of cardiac muscle cell apoptotic process
ADP transport
regulation of mitochondrial membrane permeability
transmembrane transport
negative regulation of necroptotic process
positive regulation of cell growth involved in cardiac muscle cell development
mitochondrial ADP transmembrane transport
positive regulation of mitophagy
negative regulation of mitochondrial membrane permeability involved in apoptotic process
hydrogen ion transmembrane transport
mitochondrial ATP transmembrane transport
adaptive thermogenesis
positive regulation of oxidative phosphorylation uncoupler activity
generation of precursor metabolites and energy
adenine transport
liver development
heart development
response to interleukin-1
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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