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Invitrogen
PRPF3 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-102783
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human PRPF3(Accession O43395), corresponding to amino acid residues P53-K103.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total PRPF3.
Target Information
The removal of introns from nuclear pre-mRNAs occurs on complexes called spliceosomes, which are made up of 4 small nuclear ribonucleoprotein (snRNP) particles and an undefined number of transiently associated splicing factors. PRPF3 is 1 of several proteins that associate with U4 and U6 snRNPs. The removal of introns from nuclear pre-mRNAs occurs on complexes called spliceosomes, which are made up of 4 small nuclear ribonucleoprotein (snRNP) particles and an undefined number of transiently associated splicing factors. PRPF3 is 1 of several proteins that associate with U4 and U6 snRNPs.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Hprp3p; pre-mRNA-splicing factor 3; PRP3 pre-mRNA processing factor 3 homolog; U4/U6 snRNP 90 kDa protein; U4/U6-associated RNA splicing factor; unnamed protein product
Gene Aliases: 3632413F13Rik; HPRP3; HPRP3P; PRP3; Prp3p; RP18; SNRNP90
UniProt ID: (Human) O43395, (Mouse) Q922U1
Entrez Gene ID: (Human) 9129, (Mouse) 70767, (Rat) 361995
spliceosomal tri-snRNP complex assembly
spliceosomal complex assembly
RNA splicing, via transesterification reactions
spliceosomal snRNP assembly
spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
mRNA splicing, via spliceosome
mRNA processing
RNA splicing
biological_process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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