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Invitrogen
RSF1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-102998
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human RSF1(Accession Q96T23), corresponding to amino acid residues E388-G438.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total RSF1.
Target Information
RSF1 is required for assembly of regular nucleosome arrays by the RSF chromatin remodelling complex. Rsf1 facilitates transcription of hepatitis B virus (HBV) genes by the pX transcription activator. In case of infection by HBV, together with pX, it represses TNF-alpha induced NF-kappaB transcription activation. Rsf1 represses transcription when artificially recruited to chromatin by fusion to a heterogeneous DNA binding domain. Rsf1 interacts with SMARCA5/SNF2H to form the RSF complex and also binds the HBV pX/HBx protein, which is required to activate transcription of the viral genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: HBV pX-associated protein 8; hepatitis B virus x associated protein; hepatitis B virus x-associated protein; novel transcription coactivator; p325 subunit of RSF chromatin-remodeling complex; PHD-finger nuclear protein XAP8alpha; unnamed protein product
Gene Aliases: 4832420A03Rik; C030033M12Rik; Gm164; HBXAP; p325; RSF-1; XAP8
UniProt ID: (Human) Q96T23
Entrez Gene ID: (Human) 51773, (Rat) 308839, (Mouse) 233532
chromatin organization
nucleosome assembly
chromatin remodeling
DNA-templated transcription, initiation
regulation of transcription, DNA-templated
heterochromatin assembly
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of viral transcription
negative regulation of DNA binding
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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