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FIGURE: 1 / 2
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Antibody detects endogenous levels of total RNF19A.
This gene encodes a member of the ring between ring fingers (RBR) protein family, and the encoded protein contains two RING-finger motifs and an in between RING fingers motif. This protein is an E3 ubiquitin ligase that is localized to Lewy bodies, and ubiquitylates synphilin-1, which is an interacting protein of alpha synuclein in neurons. The encoded protein may be involved in amyotrophic lateral sclerosis and Parkinson's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: double ring-finger protein; gametogenesis-expressed protein GEG-154; GEG-154; protein p38 interacting with transcription factor Sp1; ring finger protein (C3HC4 type) 19; ring finger protein 19A, E3 ubiquitin protein ligase; ring-IBR-ring domain containing protein Dorfin; UBCM4-interacting protein 117; ubiquitin conjugating enzyme 7 interacting protein 2; UIP117; unnamed protein product; XY body protein; XYbp
Gene Aliases: Dorfin; RNF19; Ubce7ip2; UIP117; XYbp
UniProt ID: (Human) Q9NV58, (Mouse) P50636
Entrez Gene ID: (Human) 25897, (Mouse) 30945
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