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Invitrogen

ZFP36L1 Polyclonal Antibody

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ZFP36L1 Polyclonal Antibody

Product Details

PA5-104284

Applications
Tested Dilution
Publications

Western Blot (WB)

1:1,000
-

Immunocytochemistry (ICC/IF)

1:100-1:500
-
Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human ZFP36L1(Accession Q07352), corresponding to amino acid residues L220-G270.
3D Epitope / Immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Amount

100 µg

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2853595

Product Specific Information

Antibody detects endogenous levels of total TIS11B.

Target Information

This gene is a member of the TIS11 family of early response genes. Family members are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. The gene is well conserved across species and has a promoter that contains motifs seen in other early-response genes. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Berg36; butyrate response factor 1; early response factor Berg36; EGF-response factor 1; ERF-1; TPA-induced sequence 11b; unnamed protein product; ZFP36 ring finger protein like 1; ZFP36-like 1; zinc finger protein 36, C3H type-like 1; zinc finger protein 36, C3H1 type-like 1; zinc finger protein, C3H type, 36-like 1

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Gene Aliases: Berg36; BRF1; cMG1; D530020L18Rik; ERF-1; ERF1; RNF162B; TIS11B

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UniProt ID: (Human) Q07352, (Mouse) P23950

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Entrez Gene ID: (Human) 677, (Mouse) 12192

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Function(s)
translation repressor activity, nucleic acid binding RNA binding mRNA binding protein binding mRNA 3'-UTR AU-rich region binding metal ion binding 14-3-3 protein binding protein-RNA sequence-specific adaptor activity
Process(es)
MAPK cascade nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay nuclear-transcribed mRNA poly(A) tail shortening vasculogenesis proepicardium development mRNA catabolic process regulation of translation apoptotic process heart development cell proliferation response to wounding regulation of gene expression regulation of keratinocyte proliferation negative regulation of translation neural tube development nuclear-transcribed mRNA catabolic process, deadenylation-independent decay regulation of mRNA 3'-end processing cellular response to insulin stimulus T cell differentiation in thymus multicellular organism growth p38MAPK cascade regulation of mRNA stability protein kinase B signaling cellular response to fibroblast growth factor stimulus regulation of B cell differentiation positive regulation of fat cell differentiation regulation of keratinocyte differentiation negative regulation of erythrocyte differentiation positive regulation of monocyte differentiation regulation of myoblast differentiation mesendoderm development embryonic organ development mRNA transport chorio-allantoic fusion spongiotrophoblast layer development 3'-UTR-mediated mRNA destabilization ERK1 and ERK2 cascade cellular response to cAMP cellular response to tumor necrosis factor cellular response to epidermal growth factor stimulus cellular response to peptide hormone stimulus cellular response to glucocorticoid stimulus cellular response to hypoxia cellular response to salt stress cellular response to transforming growth factor beta stimulus regulation of stem cell proliferation cellular response to raffinose positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay negative regulation of mitotic cell cycle phase transition regulation of keratinocyte apoptotic process positive regulation of intracellular mRNA localization
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