Hamburger Menu Button
Thermo Fisher Scientific Logo
Sign in
Don't have an account ? Create Account
  • Products
    • Antibodies
    • Cell Culture Media
    • Chemicals
    • Chromatography Columns and Cartridges
    • Lab Equipment
    • Lab Plasticware and Supplies
    • Microplates
    • Oligos, Primers, Probes and Genes
    • TaqMan Real-Time PCR Assays
    • Greener Products
    • See all product categories
  • Applications
    • Bioprocessing
    • Cell Culture and Transfection
    • Cell and Gene Therapy
    • Chromatography
    • Molecular Testing
    • Digital Solutions
    • DNA and RNA Extraction and Analysis
    • Spectroscopy, Elemental and Isotope Analysis
    • See all applications and techniques
  • Services
    • 360° CDMO and CRO Solutions
    • CDMO Services
    • CRO Services
    • Custom Services
    • Financial and Leasing Services
    • Instrument Services
    • Lab Informatics
    • OEM and Commercial Supply
    • Training Services
    • Unity Lab Services
    • See all services
  • Help and Support
    • How to Order
    • Instrument Support
    • Learning Centers
    • Register for an Account
    • Technical Support Centers
    • See all help and support topics
  • Popular
    • TaqMan Real-Time PCR Assays
      TaqMan Real-Time PCR Assays
    • Antibodies
      Antibodies
    • Oligos, Primers & Probes
      Oligos, Primers & Probes
    • GeneArt Gene Synthesis
      GeneArt Gene Synthesis
    • Cell Culture Plastics
      Cell Culture Plastics
  • Who We Serve
    • Biotech
    • Biopharma
    • CDMO
    • Lab Diagnostics
    • Industrial and Applied Sciences
  • New Products
  • Promotions
  • Contact Us
  • Quick Order
  • Order Status and Tracking
  • Documents and Certificates
Thermo Fisher Scientific Logo

Search

Search All
Search button
          • Order Status
          • Quick Order
          • Promos
          • Sign in
            Sign in
            Don't have an account ? Create Account
            • Account
            • Check Order Status
            • Aspire Member Program
            • Connect: Lab, Data, Apps
            • Custom Products & Projects
            • Services Central
          • Primary Antibodies ›
          • SOX9 Antibodies

          Invitrogen

          Phospho-SOX9 (Ser181) Polyclonal Antibody

          View all (66) SOX9 antibodies

          {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}

          {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

          Datasheet
          Certificates
          Protocols
          Questions & Answers
          Datasheet
          Certificates
          Protocols
          Questions & Answers
          Datasheet
          Certificates
          Protocols
          Questions & Answers

          Cite Phospho-SOX9 (Ser181) Polyclonal Antibody

          Additional Information:

          {{$ctrl.isSkuNotesCollapsed ? 'View more' : 'View less'}}
          • Antibody Testing Data (3)
          Phospho-SOX9 (Ser181) Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          Phospho-SOX9 (Ser181) Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 3

          {{ $ctrl.currentElement.advancedVerification.fullName }}
          {{ $ctrl.currentElement.advancedVerification.text }}

          Phospho-SOX9 (Ser181) Antibody (PA5-104914) in ICC/IF

          Immunofluorescent analysis of Phospho-SOX9 (Ser181) in A549 cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% saponin, blocked with 10% serum (45 min, 37°C) incubated with Phospho-SOX9 (Ser181) polyclonal antibody (Product # PA5-104914) using a dilution of 1:400 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 at a dilution of 1:600. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
          PMID: {{$ctrl.currentElement.benchSciPubmedId}}
          View Product

          {{$ctrl.videoDesc}}

          {{$ctrl.videoLongDesc}}

          Phospho-SOX9 (Ser181) Antibody in Immunocytochemistry (ICC/IF)
          Phospho-SOX9 (Ser181) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Phospho-SOX9 (Ser181) Antibody in Western Blot (WB)

          Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

          Phospho-SOX9 (Ser181) Polyclonal Antibody

          Product Details

          PA5-104914

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:2,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:200
          -

          Immunocytochemistry (ICC/IF)

          1:100-1:500
          -
          Product Specifications

          Species Reactivity

          Chicken, Human, Mouse

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          A synthesized peptide derived from human SOX9(Accession P48436), corresponding to amino acid residues around phosphorylated Ser181.
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Amount

          100 µg

          Purification

          sequential chromatography

          Storage buffer

          PBS, pH 7.4, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2816387

          Product Specific Information

          Antibody detects endogenous levels of SOX9 only when phosphorylated at Serine 181.

          Target Information

          SOX9 has a role in sex determination and differentiation of Sertoli cells. It is involved in chondrogenesis and regulates the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes. Translocation of this gene can cause campomelic dysplasia. SOX9 is involved in the formation of testes from the indifferent fetal gonads. It is a major molecular component of the neuron-glia switch in developing spinal cord. During normal development, SOX9 allows the prostate epithelium to outgrow into the mesenchyme and then provides basal cell support for development and maintenance of the luminal epithelium. These functions of SOX9 are subverted in prostate cancer to support tumor growth and invasion. SOX9 may direct the formation of neural crest precursors and the development of a range of neural crest derivative. It has a transcriptional regulation in melanin production in cells. Northern blot analysis shows its expression on adult testis, adult heart, and fetal brain.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

          Have you cited this product in a publication?
          Let us know so we can reference it here.
          Cite this product

          Bioinformatics

          Protein Aliases: SOX 9; SOX9; SRY (sex determining region Y)-box9; SRY (sex-determining region Y)-box 9 protein; SRY-box 9; SRY-Box 9 ; SRY-box containing gene 9; SRY-related HMG-box, gene 9; unnamed protein product

          View more View less

          Gene Aliases: 2010306G03Rik; CMD1; CMPD1; ENH13; mKIAA4243; mSox9; SOX-9; SRA1; SRXX2; SRXY10; TESCO

          View more View less

          UniProt ID: (Chicken) P48434, (Human) P48436, (Mouse) Q04887

          View more View less

          Entrez Gene ID: (Chicken) 374148, (Human) 6662, (Mouse) 20682

          View more View less

          Function(s)
          RNA polymerase II core promoter proximal region sequence-specific DNA binding core promoter proximal region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding chromatin binding protein binding beta-catenin binding protein kinase A catalytic subunit binding ubiquitin-like protein conjugating enzyme binding pre-mRNA intronic binding transcription regulatory region sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding DNA binding transcription factor activity, sequence-specific DNA binding bHLH transcription factor binding sequence-specific DNA binding sequence-specific double-stranded DNA binding
          Process(es)
          negative regulation of transcription from RNA polymerase II promoter cartilage condensation ossification branching involved in ureteric bud morphogenesis neural crest cell migration positive regulation of protein phosphorylation morphogenesis of an epithelium positive regulation of mesenchymal cell proliferation chondrocyte differentiation negative regulation of immune system process heart valve development aortic valve morphogenesis heart valve formation endocardial cushion morphogenesis growth plate cartilage chondrocyte growth nucleosome assembly chromatin remodeling transcription, DNA-templated cytoskeleton organization epidermal growth factor receptor signaling pathway Notch signaling pathway spermatogenesis central nervous system development heart development male gonad development regulation of cell cycle process positive regulation of epithelial cell migration neural crest cell fate specification positive regulation of phosphatidylinositol 3-kinase signaling male germ-line sex determination cAMP-mediated signaling extracellular matrix organization negative regulation of bone mineralization negative regulation of epithelial cell differentiation positive regulation of epithelial cell differentiation notochord development otic vesicle formation endocrine pancreas development negative regulation of chondrocyte differentiation positive regulation of chondrocyte differentiation lacrimal gland development positive regulation of collagen biosynthetic process protein localization to nucleus somatic stem cell population maintenance intrahepatic bile duct development neural crest cell delamination protein kinase B signaling negative regulation of myoblast differentiation negative regulation of osteoblast differentiation positive regulation of protein catabolic process positive regulation of transcription from RNA polymerase II promoter negative regulation of fatty acid oxidation negative regulation of photoreceptor cell differentiation embryonic digestive tract development oligodendrocyte differentiation homeostasis of number of cells within a tissue positive regulation of epithelial cell proliferation negative regulation of epithelial cell proliferation Sertoli cell development astrocyte fate commitment limb bud formation retinal rod cell differentiation transdifferentiation epithelial tube branching involved in lung morphogenesis lung epithelial cell differentiation bronchus cartilage development trachea cartilage development intestinal epithelial structure maintenance regulation of cell proliferation involved in tissue homeostasis regulation of cartilage development regulation of branching involved in lung morphogenesis lung smooth muscle development ERK1 and ERK2 cascade Harderian gland development response to fatty acid cellular response to mechanical stimulus cellular response to retinoic acid cellular response to interleukin-1 cellular response to epidermal growth factor stimulus cellular response to heparin cellular response to transforming growth factor beta stimulus cellular response to BMP stimulus renal vesicle induction ureter urothelium development ureter smooth muscle cell differentiation ureter morphogenesis metanephric nephron tubule formation negative regulation of canonical Wnt signaling pathway cochlea morphogenesis positive regulation of branching involved in ureteric bud morphogenesis positive regulation of neural crest formation anterior head development cell-cell adhesion positive regulation of extracellular matrix assembly positive regulation of cartilage condensation positive regulation of chondrocyte proliferation negative regulation of pri-miRNA transcription from RNA polymerase II promoter negative regulation of bone development positive regulation of male gonad development positive regulation of cell proliferation involved in heart morphogenesis positive regulation of mesenchymal stem cell differentiation regulation of epithelial cell proliferation involved in lung morphogenesis negative regulation of mesenchymal cell apoptotic process skeletal system development cell fate specification epithelial to mesenchymal transition tissue homeostasis hair follicle development heart valve morphogenesis chondrocyte differentiation involved in endochondral bone morphogenesis chondrocyte hypertrophy signal transduction positive regulation of cell proliferation gene expression positive regulation of gene expression negative regulation of ossification prostate gland development mammary gland development regulation of cell proliferation regulation of apoptotic process negative regulation of apoptotic process negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated cartilage development Sertoli cell differentiation retina development in camera-type eye epithelial cell proliferation involved in prostatic bud elongation positive regulation of cartilage development morphogenesis of a branching epithelium protein-containing complex assembly negative regulation of biomineral tissue development otic vesicle development metanephric tubule development positive regulation of kidney development negative regulation of beta-catenin-TCF complex assembly chondrocyte development regulation of transcription, DNA-templated regulation of transcription from RNA polymerase II promoter negative regulation of cell proliferation regulation of gene expression negative regulation of gene expression neural crest cell development cell differentiation regulation of cell adhesion male sex determination cell fate commitment regulation of cell differentiation endochondral bone morphogenesis prostate gland morphogenesis ureter development
          It has to be done as per old AB suggested Products section.

          Disclaimer

          Close

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          guarantee_icon

          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

          Learn more
          help_icon

          We're here to help

          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

          Contact tech support
          Ordering Plus Icon Minus Icon
          • Order Status
          • Order Help
          • Quick Order
          • Supply Center
          • eProcurement
          Support Plus Icon Minus Icon
          • Help and Support
          • Contact Us
          • Technical Support Centers
          • Documents and Certificates
          • Report a Site Issue
          Resources Plus Icon Minus Icon
          • Learning Centers
          • Promotions
          • Events and Webinars
          • Social Media
          About Thermo Fisher Plus Icon Minus Icon
          • About Us About Us
          • Careers Careers
          • Investors Investors
          • News News
          • Social Responsibility Social Responsibility
          • Trademarks
          • Consumer Health Data Privacy Policy Consumer Health Data Privacy Policy
          • Policies and Notices
          Our Portfolio Plus Icon Minus Icon
          • Thermo Scientific
          • Applied Biosystems
          • Invitrogen
          • Gibco
          • Ion Torrent
          • Fisher Scientific
          • Unity Lab Services
          • Patheon
          • PPD
          • Terms & Conditions
          • Privacy Notice
          • Price & Freight Policy
          © 2006-2026 Thermo Fisher Scientific Inc. All rights reserved. All trademarks are the property of Thermo Fisher Scientific and its subsidiaries unless otherwise specified.
          United States flag icon
          United States

          Your items have has been added!


          Host server : magellan-search-blue-5bc99cc877-gh2m7:80/100.66.74.151:80.
          git-commit: a70b05477dc28cec55d7eafa2ce360191b99e591
          git-url: https://github.com/thermofisher/magellan-search
          git-branch: release/2.58.0-2026.09.99-1.0