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Invitrogen
Phospho-CRMP2 (Thr514) Polyclonal Antibody
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FIGURE: 1 / 3
Phospho-CRMP2 (Thr514) Antibody (PA5-105010) in ICC/IF
Immunofluorescent analysis of Phospho-CRMP2 (Thr514) in PC12 cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% saponin, blocked with 10% serum (45 min, 37°C) incubated with Phospho-CRMP2 (Thr514) polyclonal antibody (Product # PA5-105010) using a dilution of 1:400 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 at a dilution of 1:600.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-105010
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human DPYSL2(Accession Q16555), corresponding to amino acid residues around phosphorylated Thr514.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
sequential chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of CRMP2 only when phosphorylated at Threonine 514.
Target Information
Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: collapsin response mediator protein 2; collapsin response mediator protein hCRMP-2; CRMP-2; DPYL2; DRP-2; turned on after division, 64 kDa protein; ULIP-2; unc-33-like phosphoprotein 2; unnamed protein product
Gene Aliases: CRMP-2; CRMP2; DHPRP2; DRP-2; DRP2; Musunc33; N2A3; TOAD-64; ULIP-2; ULIP2
UniProt ID: (Human) Q16555, (Rat) P47942, (Mouse) O08553
Entrez Gene ID: (Human) 1808, (Rat) 25416, (Mouse) 12934
nucleobase-containing compound metabolic process
pyrimidine nucleobase catabolic process
endocytosis
cytoskeleton organization
signal transduction
nervous system development
response to amphetamine
response to xenobiotic stimulus
regulation of neuron projection development
positive regulation of glutamate secretion
spinal cord development
olfactory bulb development
regulation of axon extension
response to cocaine
regulation of neuron differentiation
synaptic vesicle transport
regulation of postsynapse assembly
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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