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Invitrogen
Phospho-GDF9 (Tyr394) Polyclonal Antibody
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FIGURE: 1 / 1
Phospho-GDF9 (Tyr394) Antibody (PA5-105310) in WB
Western blot analysis of Phospho-GDF9 (Tyr394) in HL60 cell lysate (Lane 1: treated with phospho-blocking peptide; Lane 2: treated with non-phospho-blocking peptide). Samples were incubated with Phospho-GDF9 (Tyr394) polyclonal antibody (Product # PA5-105310).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-105310
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human GDF9(Accession O60383), corresponding to amino acid residues around phosphorylated Tyr394.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
sequential chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of GDF9 only when phosphorylated at Tyr394.
Target Information
GDF9 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues.Growth factors synthesized by ovarian somatic cells directly affect oocyte growth and function. GDF9 is expressed in oocytes and is thought to be required for ovarian folliculogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: growth factor of the TGF-beta/activin family; oocyte-specific secretory protein; unnamed protein product
Gene Aliases: Gdf-9; POF14
UniProt ID: (Human) O60383, (Mouse) Q07105
Entrez Gene ID: (Human) 2661, (Rat) 59304, (Mouse) 14566
ovarian cumulus expansion
oocyte growth
blastocyst development
transmembrane receptor protein serine/threonine kinase signaling pathway
positive regulation of cell proliferation
negative regulation of cell growth
embryonic cleavage
positive regulation of MAP kinase activity
positive regulation of cyclin-dependent protein serine/threonine kinase activity
positive regulation of oocyte maturation
regulation of progesterone secretion
transforming growth factor beta receptor signaling pathway
female gamete generation
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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