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Invitrogen

Phospho-SMC3 (Ser1083) Polyclonal Antibody

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Phospho-SMC3 (Ser1083) Polyclonal Antibody

Product Details

PA5-106163

Applications
Tested Dilution
Publications

Western Blot (WB)

1:1,000-1:3,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human SMC3(Accession Q9UQE7), corresponding to amino acid residues around phosphorylated Ser1083.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

sequential chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2817561

Product Specific Information

Antibody detects endogenous levels of Bamacan only when phosphorylated at Ser1083.

Target Information

This gene belongs to the SMC3 subfamily of SMC proteins. The encoded protein occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein. The nuclear form, known as structural maintenance of chromosomes 3, is a component of the multimeric cohesin complex that holds together sister chromatids during mitosis, enabling proper chromosome segregation. Post-translational modification of the encoded protein by the addition of chondroitin sulfate chains gives rise to the secreted proteoglycan bamacan, an abundant basement membrane protein.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Bamacan; basement membrane chondroitin sulfate proteoglycan; Basement membrane-associated chondroitin proteoglycan; Chondroitin sulfate proteoglycan 6; chondroitin sulfate proteoglycan 6 (bamacan); Chromosome segregation protein SmcD; Chromosome-associated polypeptide; hCAP; Mad member-interacting protein 1; SMC family; SMC protein 3; structural maintenace of chromosomes 3; Structural maintenance of chromosomes protein 3; unnamed protein product

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Gene Aliases: BAM; Bamacan; BMH; CDLS3; CSPG6; HCAP; Mmip1; SMC-3; SMC3; SMC3L1; SmcD

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UniProt ID: (Human) Q9UQE7, (Mouse) Q9CW03

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Entrez Gene ID: (Human) 9126, (Mouse) 13006, (Rat) 29486

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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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