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Invitrogen
ST6GAL1 Polyclonal Antibody
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FIGURE: 1 / 5
ST6GAL1 Antibody (PA5-106647) in IHC (P)
Immunohistochemistry analysis of ST6GAL1 in human colorectal cancer. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with ST6GAL1 polyclonal antibody (Product # PA5-106647) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-106647
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human ST6GAL1(Accession P15907), corresponding to amino acid residues K177-T227.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total ST6GAL1.
Target Information
The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein, which is normally found in the Golgi but which can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CDw75, and CD76. This protein is a member of glycosyltransferase family 29. Three transcript variants encoding two different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alpha 2,6-ST 1; B-cell antigen CD75; beta-galactoside alpha 2,6-sialyltransferase precursor; CMP-N-acetylneuraminate beta-galactosamide alpha-2,6-sialyltransferase; CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1; putative; sialyltransferase 1 (beta-galactoside alpha-2,6-sialyltransferase); Sialyltransferase 1 (beta-galactoside alpha-2,6-sialytransferase); Sialyltransferase 1 (beta-galactoside alpha-26-sialytransferase); ST6 beta-galactosamide alpha-2,6-sialyltranferase 1; ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1; ST6Gal I; ST6GalI; unnamed protein product
Gene Aliases: CDw75; SIAT1; St6gal; St6Gal-I; ST6GalI; ST6N
UniProt ID: (Human) P15907, (Rat) P13721, (Mouse) Q64685
Entrez Gene ID: (Human) 6480, (Rat) 25197, (Mouse) 20440
N-acetylneuraminate metabolic process
protein N-linked glycosylation
glycoprotein biosynthetic process
positive regulation of mononuclear cell proliferation
response to ethanol
negative regulation of chemotaxis
sialylation
regulation of substrate adhesion-dependent cell spreading
protein sialylation
negative regulation of macrophage apoptotic process
negative regulation of brown fat cell differentiation
O-glycan processing
viral protein processing
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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