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Invitrogen
SYT11 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-106754
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human SYT11(Accession Q9BT88), corresponding to amino acid residues H182-I232.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total SYT11.
Target Information
This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that are known calcium sensors and mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. The encoded protein is also a substrate for ubiquitin-E3-ligase parkin. The gene has previously been referred to as synaptotagmin XII but has been renamed synaptotagmin XI to be consistent with mouse and rat official nomenclature. [provided by RefSeq, Apr 2010].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: KIAA0080; membrane trafficking protein; putative membrane trafficking protein; synaptotagmin XI; sytXI; unnamed protein product
Gene Aliases: 1500004A13Rik; 3632445O20Rik; 5430404N14Rik; 6530420C11Rik; sytXI
UniProt ID: (Human) Q9BT88, (Rat) O08835, (Mouse) Q9R0N3
Entrez Gene ID: (Human) 23208, (Rat) 60568, (Mouse) 229521
plasma membrane repair
negative regulation of cytokine production
vesicle fusion
autophagy
learning
memory
response to wounding
vesicle-mediated transport
regulation of calcium ion-dependent exocytosis
regulation of endocytosis
negative regulation of interleukin-6 production
negative regulation of tumor necrosis factor production
negative regulation of dopamine secretion
negative regulation of catecholamine secretion
negative regulation of endocytosis
negative regulation of phagocytosis
establishment of vesicle localization
calcium-dependent activation of synaptic vesicle fusion
negative regulation of clathrin-mediated endocytosis
regulation of synaptic vesicle endocytosis
negative regulation of synaptic vesicle endocytosis
regulation of defense response to bacterium
negative regulation of microglial cell activation
negative regulation of membrane invagination
positive regulation of protein localization to phagocytic vesicle
negative regulation of clathrin coat assembly
calcium ion regulated lysosome exocytosis
negative regulation of neurotransmitter secretion
negative regulation of secretion by cell
regulation of phagosome maturation
regulation of dopamine secretion
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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