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Invitrogen
HuR Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-106881
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human ELAVL1(Accession Q15717), corresponding to amino acid residues L145-L195.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total ELAVL1.
Target Information
The protein encoded by this gene is a member of the ELAVL protein family. This encoded protein contains 3 RNA-binding domains and binds cis-acting AU-rich elements. It destabilizes mRNAs and thereby regulates gene expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ELAV (embryonic lethal, abnormal vision)-like 1 (Hu antigen R); ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R); ELAV like 1; elav-like generic protein; embryonic lethal, abnormal vision, drosophila, homolog-like 1; Hu antigen R; HU-antigen A; hu-antigen R; Human antigen R; melG; mRNA-stabilizing factor HuR; unnamed protein product
Gene Aliases: 2410055N02Rik; ELAV1; Hua; HUR; MelG
UniProt ID: (Human) Q15717, (Rat) B5DF91, (Mouse) P70372
Entrez Gene ID: (Human) 1994, (Rat) 363854, (Mouse) 15568
lncRNA-mediated post-transcriptional gene silencing
protein import into nucleus
cell proliferation
response to glucose
positive regulation of autophagy
posttranscriptional gene silencing
positive regulation of superoxide anion generation
regulation of mRNA stability
positive regulation of translation
positive regulation of autophagosome size
mRNA stabilization
protein homooligomerization
negative regulation of gene silencing by miRNA
mRNA destabilization
3'-UTR-mediated mRNA stabilization
regulation of stem cell population maintenance
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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