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FIGURE: 1 / 4
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Antibody detects endogenous levels of total ZFYVE9.
Early endosomal protein that functions to recruit SMAD2/SMAD3 to intracellular membranes and to the TGF-beta receptor. Plays a significant role in TGF-mediated signaling by regulating the subcellular location of SMAD2 and SMAD3 and modulating the transcriptional activity of the SMAD3/SMAD4 complex. Possibly associated with TGF-beta receptor internalization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: MAD, mothers against decapentaplegic homolog interacting protein, receptor activation anchor; MADH-interacting protein; novel serine protease; protein phosphatase 1, regulatory subunit 173; smad anchor for receptor activation; unnamed protein product; ZFYVE9; zinc finger, FYVE domain containing 9
Gene Aliases: MADHIP; NSP; PPP1R173; SARA; SMADIP
UniProt ID: (Human) O95405
Entrez Gene ID: (Human) 9372, (Mouse) 230597
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