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Invitrogen
CaV2.3 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-109296
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide within rat CaV23 aa 875-924.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol, 0.2% BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles, store in dark
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Control: Rat brain tissue, human kidney tissue, human placenta tissue, mouse brain tissue, 293T.
Target Information
The expression of multiple classes of voltage dependent calcium channels (VDCCs) allows neurons to tailor calcium signaling to functionally discrete cellular regions. Although N-Type VDCCs exist before birth which is consistent with a role in migration, most N-Type VDCCs subunit expression is postnatal and is important in the genesis of synaptic transmission in discrete hippocampal fields.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BII; brain calcium channel II; calcium channel, L type, alpha-1 polypeptide; calcium channel, R type, alpha-1 polypeptide; calcium channel, voltage-dependent, L type, alpha 1E subunit; calcium channel, voltage-dependent, R type, alpha 1E subunit; CaV2.3; RBE-II; RBE2; voltage gated calcium channel alpha1E subunit; voltage-dependent calcium channel alpha 1E subunit; voltage-dependent calcium channel alpha1-E subunit; voltage-gated calcium channel alpha subunit Cav2.3; voltage-gated calcium channel subunit alpha Cav2.3
Gene Aliases: BII; CACH6; CACHA1E; CACNL1A6; Cav2.3; DEE69; EIEE69; gm139
UniProt ID: (Human) Q15878
Entrez Gene ID: (Human) 777, (Rat) 54234
ion channel activity
voltage-gated calcium channel activity
calcium ion binding
high voltage-gated calcium channel activity
voltage-gated cation channel activity
low voltage-gated calcium channel activity
voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels
ion transport
chemical synaptic transmission
transmembrane transport
calcium ion transmembrane transport
calcium ion import across plasma membrane
behavioral fear response
regulation of heart rate
calcium ion transport
locomotory behavior
visual learning
transmission of nerve impulse
sensory perception of pain
sperm motility
positive regulation of insulin secretion involved in cellular response to glucose stimulus
glucose homeostasis
fear response
response to pain
behavioral response to pain
neurological system process
regulation of insulin secretion involved in cellular response to glucose stimulus
calcium ion import
regulation of somatostatin secretion
regulation of presynaptic cytosolic calcium ion concentration
regulation of synaptic vesicle exocytosis
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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