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Invitrogen
RNF31 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-110309
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 500-700 of human RNF31 (NP_060469.4).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1.54 mg/mL
Amount
154 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: AAGACPEEIF SALQYSGTEV PLQWLRSELP YVLEMVAELA GQQDPGLGAF SCQEARRAWL DRHGNLDEAV EECVRTRRRK VQELQSLGFG PEEGSLQALF QHGGDVSRAL TELQRQRLEP FRQRLWDSGP EPTPSWDGPD KQSLVRRLLA VYALPSWGRA ELALSLLQET PRNYELGDVV EAVRHSQDRA FLRRLLAQEC A
Target Information
Lyn proto oncogene (Lcl/Yes related novel protein tyrosine kinase) is encoded by the Lyn gene located on chromosome 8 in humans and belongs to the Src family kinase. It is a non-receptor tyrosine kinase that acts as a mediator in transducing cellular signaling. The most well studied expression of Lyn is in hematopoietic cell types, both lymphoid and myeloid cells with exclusion in T lymphocytes. It has also been observed that Lyn plays diverse roles such as in regulation of B cell receptor signaling, mast cell signaling and Epithelial - Mesenchymal Transition (EMT).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: E3 ubiquitin ligase; FLJ23501; HOIL-1-interacting protein; MGC19975; putative Ariadne-like ubiquitin ligase; RING-type E3 ubiquitin transferase RNF31; unnamed protein product; zinc in-between-RING-finger ubiquitin-associated domain protein
Gene Aliases: Flj10111; HOIP; IMD115; mFLJ00217; Paul; ZIBRA
UniProt ID: (Human) Q96EP0, (Mouse) Q924T7
Entrez Gene ID: (Human) 55072, (Mouse) 268749
protein polyubiquitination
cell surface receptor signaling pathway
I-kappaB kinase/NF-kappaB signaling
protein ubiquitination
CD40 signaling pathway
tumor necrosis factor-mediated signaling pathway
defense response to bacterium
positive regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of I-kappaB kinase/NF-kappaB signaling
T cell receptor signaling pathway
negative regulation of necroptotic process
protein linear polyubiquitination
positive regulation of xenophagy
positive regulation of establishment of protein localization to mitochondrion
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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