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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: DPTPTMRDVN KKFSVRYFLN LVLVDEEDRR YFKQQEIILW RKAPEKLRKQ RTNFHQRFES PESQASAEQP EM
This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex. Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases:
essential for embryogenesis; FLJ12930; H beta 58; h
Gene Aliases: HB58; Hbeta58; PEP8A; VPS26
UniProt ID: (Human) O75436, (Rat) Q6AY86, (Mouse) P40336
Entrez Gene ID: (Human) 9559, (Rat) 361846, (Mouse) 30930
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