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Invitrogen
NLGN4X Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-110639
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Protein corresonding to Human NLGN4X. Recombinant protein control fragment (Product #RP-92142).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.30 mg/mL
Amount
30 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: QYPVVNTNYG KIRGLRTPLP NEILGPVEQY LGVPYASPPT GERRFQPPEP PSSWTGIRNT TQFAAVCPQH LDERSLLHDM LPIWFTANLD TLMTYVQDQN EDCLYLNIYV PTEDDIHDQN SKKPVMVYIH GGSYMEGTGN MIDGS
Highest antigen sequence indentity to the following orthologs: Rat - 70%, Mouse - 71%.
Target Information
Neuroligin-4, X linked (also known as NLGN4X, NLGN4, Neuroligin-4, and Neuroligin 4X) is a postsynaptic cell-adhesion molecule that interacts with presynaptic cell-surface neurexins. These interactions bridge together the synaptic cleft and have an essential role in synaptic transmissions between neurons. There are 5 neuroligin genes in humans: NLGN1, NLGN2, NLGN3, NLGN4X, and NLGN4Y. Mutations in NLGN3 and NLGN4X are linked to Autism Spectrum Disorders (ASD). The expression of neuroligin-4, X-linked has been reported on human pluripotent stem cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: HLNX; MGC22376; NLGN; unnamed protein product
Gene Aliases: ASPGX2; AUTSX2; HLNX; HNL4X; NLGN4
UniProt ID: (Human) Q8N0W4
Entrez Gene ID: (Human) 57502
brainstem development
neuron cell-cell adhesion
synapse assembly
learning
cerebellum development
neuron differentiation
adult behavior
social behavior
organ growth
cell-cell junction organization
modulation of synaptic transmission
synapse organization
regulation of synapse assembly
vocalization behavior
negative regulation of excitatory postsynaptic potential
presynaptic membrane assembly
presynapse assembly
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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