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Invitrogen
GPD1L Polyclonal Antibody
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FIGURE: 1 / 1
GPD1L Antibody (PA5-114389) in WB
Western blot analysis of GPD1L in the following samples: Lane 1: human placenta issue lysates, Lane 2: human PC-3 whole cell lysates, Lane 3: human U-87MG whole cell lysates, Lane 4: human HL-60 whole cell lysates, Lane 5: human HepG2 whole cell lysates, Lane 6: human A549 whole cell lysates, Lane 7: human Caco-2 whole cell lysates, Lane 8: human K562 whole cell lysates, Lane 9: rat heart issue lysates, Lane 10: mouse RAW246.7 whole cell lysates. Samples consisting of 50 µg (reducing conditions) of protein was separated with 5-20% SDS-PAGE... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-114389
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E.coli-derived human GPD1L recombinant protein (Position: A19-T351).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Lyophilized
Concentration
500 µg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS with 4mg trehalose
Contains
0.05mg sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human placenta issue, human PC-3 whole cell, human U-87MG whole cell, human HL-60 whole cell, human HepG2 whole cell, human A549 whole cell, human Caco-2 whole cell, human K562 whole cell, rat heart issue, mouse RAW2467 whole cell.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Target Information
The protein encoded by this gene catalyzes the conversion of sn-glycerol 3-phosphate to glycerone phosphate. The encoded protein is found in the cytoplasm, associated with the plasma membrane, where it binds the sodium channel, voltage-gated, type V, alpha subunit (SCN5A). Defects in this gene are a cause of Brugada syndrome type 2 (BRS2) as well as sudden infant death syndrome (SIDS).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: glycerol-3-phosphate dehydrogenase 1 like 1; KIAA0089; unnamed protein product
Gene Aliases: 2210409H23Rik; D9Ertd660e; GPD1-L; Gpd1l1; RGD1560123
UniProt ID: (Human) Q8N335, (Mouse) Q3ULJ0
Entrez Gene ID: (Human) 23171, (Mouse) 333433, (Rat) 363159
protein binding
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
sodium channel regulator activity
protein homodimerization activity
ion channel binding
glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NAD binding
glycerol-3-phosphate dehydrogenase (NAD+) activity
regulation of heart rate
carbohydrate metabolic process
glycerol-3-phosphate metabolic process
positive regulation of sodium ion transport
NAD metabolic process
glycerol-3-phosphate catabolic process
regulation of ventricular cardiac muscle cell membrane depolarization
ventricular cardiac muscle cell action potential
positive regulation of protein localization to cell surface
biological_process
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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