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Invitrogen
C12orf11 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-114884
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human INTS13(Accession Q9NVM9), corresponding to amino acid residues P642-E692.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total ASUN.
Target Information
Crucial regulator of the mitotic cell cycle and development. At prophase, required for dynein anchoring to the nuclear envelope important for proper centrosome-nucleus coupling. At G2/M phase, may be required for proper spindle formation and execution of cytokinesis. Probable component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing (PubMed:23904267). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: asunder, spermatogenesis regulator; asunder, spermatogenesis regulator homolog (Drosphila); cell cycle regulator Mat89Bb homolog; germ cell tumor 1; likely orthologue of H. sapiens chromosome 12 open reading frame 11 (C12orf11); NB4 apoptosis related protein; protein asunder homolog; sarcoma antigen NY-SAR-95; spermatogenesis associated 30; spermatogenesis-associated protein 30; unnamed protein product
Gene Aliases: 4933424B01Rik; ASUN; C12orf11; GCT1; Mat89Bb; NET48; SPATA30
UniProt ID: (Human) Q9NVM9, (Mouse) Q8QZV7
Entrez Gene ID: (Human) 55726, (Rat) 690728, (Mouse) 71177
mitotic spindle organization
regulation of mitotic cell cycle
snRNA processing
sperm motility
regulation of transcription elongation from RNA polymerase II promoter
centrosome localization
regulation of fertilization
protein localization to nuclear envelope
RNA polymerase II transcription initiation surveillance
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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