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Invitrogen
CD116 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-115054
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human CSF2RA(Accession P15509), corresponding to amino acid residues T119-I169.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total CSF2RA.
Target Information
The protein encoded by this gene is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2, a cytokine which controls the production, differentiation, and function of granulocytes and macrophages. The encoded protein is a member of the cytokine family of receptors. This gene is found in the pseudoautosomal region (PAR) of the X and Y chromosomes. Multiple transcript variants encoding different isoforms have been found for this gene, with some of the isoforms being membrane-bound and others being soluble.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alpha-GM-CSF receptor; CD116 antigen; colony stimulating factor 2 receptor alpha chain; colony stimulating factor 2 receptor alpha subunit; colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage); CSF 2R; GM CSF R alpha; GM-CSF receptor alpha subunit; GM-CSF receptor alpha subunit; cytokine receptor; colony stimulating factor 2 receptor alpha low-affinity (granulocyte-macrophage); GM-CSF-R-alpha; GM-CSFRalpha; GMCSFR-alpha; GMR-alpha; granulocyte-macrophage colony stimulating receptor alpha; granulocyte-macrophage colony-stimulating factor receptor alpha chain; growth factor receptor; CD116 antigen; GM-CSF; MGC3848; MGC4838; unnamed protein product
Gene Aliases: alphaGMR; CD116; CDw116; CSF2R; CSF2RAX; CSF2RAY; CSF2RX; CSF2RY; Csfgmra; GM-CSF-R-alpha; GM-CSF-Ra; GM-CSFR; GMCSFR; GMCSFR-alpha; GMR; GMR-alpha; SMDP4
UniProt ID: (Human) P15509, (Mouse) Q00941
Entrez Gene ID: (Human) 1438, (Mouse) 12982, (Rat) 652957
JAK-STAT cascade
granulocyte-macrophage colony-stimulating factor signaling pathway
granulocyte colony-stimulating factor signaling pathway
positive regulation of leukocyte proliferation
cellular response to granulocyte macrophage colony-stimulating factor stimulus
cell surface receptor signaling pathway
positive regulation of cell proliferation
cytokine-mediated signaling pathway
positive regulation of JAK-STAT cascade
growth hormone receptor signaling pathway
response to ethanol
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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