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Invitrogen
GFR alpha-2 Polyclonal Antibody
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FIGURE: 1 / 8
GFR alpha-2 Antibody (PA5-115280) in ICC/IF
Immunocytochemistry analysis of GFR alpha-2 in HeLa cells. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-115280) at a dilution of 1:200 (1 hr at 37°C). Secondary staining was applied with mouse anti-beta tubulin; AlexaFluor 594 conjugated goat anti-rabbit IgG (Red); AlexaFluor 88 conjugated goat... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-115280
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human GFRA2(Accession O00451), corresponding to amino acid residues A167-Y217.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total GDNF Receptor alpha 2.
Target Information
GFRa-2 binds NTN and mediates activation of RET receptor tyrosine kinase by both NTN and GDNF. Thus, NTN, GFRa-2, and the Ret PTK form a complex to transduce NTN signal and to mediate NTN function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: GDNF family receptor alpha 2b; GDNF family receptor alpha 2c; GDNF re; GDNF receptor beta; GDNFR-alpha-2; GDNFR-beta; GFR alpha 2; GFR alpha-2b; GFR a-2b; GFR alpha-2c; GFR a-2c; GFR-alpha 2; GFR-alpha-2; Gfra2; glial cell line derived neurotrophic factor family receptor alpha 2; glial cell line derived neurotrophic factor receptor, beta; HpV18gp1; neurturin receptor alpha; non-signalling receptor for GDNF; NRTNR-alpha; NTNR-alpha; PI-linked cell-surface accessory protein; RET ligand 2; TGF-beta related neurotrophic factor receptor 2; neurturin/GDNF receptor; TGF-beta related neurotrophic factor receptor 2; TRN receptor, GPI-anchored; TGF-beta-related neurotrophic factor receptor 2; TRN receptor, GPI-anchored; tyrosine kinase receptor ligand 2; unnamed protein product
Gene Aliases: GDNFRB; NRTNR-ALPHA; NTNRA; RETL2; TRNR2
UniProt ID: (Human) O00451, (Mouse) O08842
Entrez Gene ID: (Human) 2675, (Mouse) 14586, (Rat) 25136
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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