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Invitrogen
IL4I1 Polyclonal Antibody
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FIGURE: 1 / 4
IL4I1 Antibody (PA5-115418) in ICC/IF
Immunocytochemistry analysis of IL4I1 in HepG2 cells. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-115418). Secondary staining was applied with mouse anti-beta tubulin (1 hr at 37°, AlexaFluor 594 conjugated goat anti-rabbit IgG (Red), AlexaFluor 488 conjugated goat anti-mouse IgG (Green) and DAPI.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-115418
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human IL4I1(Accession Q96RQ9), corresponding to amino acid residues P486-S536.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total IL4I1.
Target Information
This gene encodes a protein with limited similarity to L-amino acid oxidase which contains the conserved amino acids thought to be involved in catalysis and binding of flavin adenine dinucleotide (FAD) cofactor. The expression of this gene can be induced by interleukin 4 in B cells, however, expression of transcripts containing the first two exons of the upstream gene is found in other cell types. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Fig-1 protein; FIG1; IL4-induced protein 1; IL4I1_2; IL4I1_v2 protein; IL4I1_v2a protein; IL4I1_v2b protein; interleukin four induced 1; L-amino-acid oxidase; rCG53598-like
Gene Aliases: FIG1; hIL4I1; LAAO; LAO
UniProt ID: (Human) Q96RQ9
Entrez Gene ID: (Human) 259307, (Rat) 100360621
regulation of adaptive immune response
negative regulation of T cell mediated immune response to tumor cell
L-phenylalanine catabolic process
tryptophan catabolic process
tyrosine catabolic process
cellular amino acid catabolic process
aromatic amino acid family metabolic process
negative regulation of T cell proliferation
regulation of B cell differentiation
positive regulation of regulatory T cell differentiation
positive regulation of transcription from RNA polymerase II promoter
negative regulation of T cell activation
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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