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Invitrogen
NKAP Polyclonal Antibody
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FIGURE: 1 / 20
NKAP Antibody (PA5-115654) in IHC (P)
Immunohistochemistry analysis of NKAP in human pancreatic cancer and adjacent normal tissues. Samples were treated with formaldehyde and treated with citrate buffer for antigen retrieval, blocked, and incubated (1.5 hours at 22°C) with polyclonal antibody (Product # PA5-115654) at a dilution of 1:100. Secondary staining was applied with HRP conjugated anti-Rabbit.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-115654
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human NKAP(Accession Q8N5F7), corresponding to amino acid residues G6-L56.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total NKAP.
Target Information
NKAP is a transcriptional repressor that associates with the NOTCH (see MIM 190198) corepressor complex and is required for T-cell development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ22626; NF-kappaB activating protein; NKAP; nuclear NF-kappaB activating protein; unnamed protein product
Gene Aliases: 2610020O08Rik; MRXSHD
UniProt ID: (Human) Q8N5F7, (Rat) Q4V7C9, (Mouse) Q9D0F4
Entrez Gene ID: (Human) 79576, (Rat) 298342, (Mouse) 67050
negative regulation of transcription from RNA polymerase II promoter
mRNA splicing, via spliceosome
negative regulation of transcription, DNA-templated
positive regulation of alpha-beta T cell differentiation
stem cell population maintenance
hemopoiesis
granulocyte differentiation
T cell differentiation in thymus
hematopoietic stem cell proliferation
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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