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Invitrogen
SGTA Polyclonal Antibody
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FIGURE: 1 / 3
SGTA Antibody (PA5-115891) in ICC/IF
Immunocytochemistry analysis of SGTA in Vero cells. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-115891) at a dilution of 1:200 (1 hr at 37°C). Secondary staining was applied with mouse anti-beta tubulin; AlexaFluor 594 conjugated goat anti-rabbit IgG (Red); AlexaFluor 88 conjugated goat anti-mouse IgG (Green) and DAPI (blue) using a dilution of 1:200 (1 hr at 37°C).
Product Details
PA5-115891
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human SGTA(Accession O43765), corresponding to amino acid residues A276-E313.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total SGTA.
Target Information
This gene encodes a protein which is capable of interacting with the major nonstructural protein of parvovirus H-1 and 70-kDa heat shock cognate protein; however, its function is not known. Since this transcript is expressed ubiquitously in various tissues, this protein may serve a housekeeping function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alpha h UBP; Alpha-SGT; protein containing three tetratricopeptide repeats; SGTA; small glutamine rich tetratricopeptide repeat containing alpha; small glutamine-rich tetratricopeptide repeat (TPR) containing protein; small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha; Small glutamine-rich tetratricopeptide repeat-containing protein alpha; UBP; unnamed protein product; viral protein U-binding protein; Vpu-binding protein
Gene Aliases: 5330427H01Rik; AI194281; alphaSGT; D10Ertd190e; hSGT; SGT; SGT1; SGTA; Stg; Vpu
UniProt ID: (Human) O43765, (Mouse) Q8BJU0
Entrez Gene ID: (Human) 6449, (Mouse) 52551
biological_process
posttranslational protein targeting to membrane
ERAD pathway
tail-anchored membrane protein insertion into ER membrane
negative regulation of ERAD pathway
positive regulation of ERAD pathway
negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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