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Invitrogen
HIC5 Polyclonal Antibody
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FIGURE: 1 / 2
HIC5 Antibody (PA5-117133) in WB
Western blot analysis of HIC5 in extracts of various cell lines. Samples were incubated with HIC5 Polyclonal antibody (Product # PA5-117133) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-117133
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 120-220 of human TGFB1I1 (NP_0010359191)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.93 mg/mL
Amount
93 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Samples: HT-1080, Mouse spleen
Immunogen sequence: VASGEQKEDQ SEDKKRPSLP SSPSPGLPKA SATSATLELD RLMASLSDFR VQNHLPASGP TQPPVVSSTN EGSPSPPEPT GKGSLDTMLG LLQSDLSRRG V
Target Information
This gene encodes a coactivator of the androgen receptor, a transcription factor which is activated by androgen and has a key role in male sexual differentiation. The encoded protein is thought to regulate androgen receptor activity and may have a role to play in the treatment of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: androgen receptor coactivator 55 kDa protein; androgen receptor coactivator ARA55; androgen receptor-associated protein of 55 kDa; focal adhesion plaque protein and steroid receptor transcription coactivator; hydrogen peroxide-inducible clone 5 protein; hydrogen peroxide-inducible clone-5; TGF beta-stimulated clone 5; unnamed protein product
Gene Aliases: ARA55; HIC-5; HIC5; TSC-5
UniProt ID: (Human) O43294, (Rat) Q99PD6, (Mouse) Q62219
Entrez Gene ID: (Human) 7041, (Rat) 84574, (Mouse) 21804
cell adhesion
negative regulation of cell proliferation
positive regulation of epithelial to mesenchymal transition
positive regulation of transforming growth factor beta receptor signaling pathway
substrate adhesion-dependent cell spreading
endothelial cell migration
positive regulation of transcription, DNA-templated
positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
morphogenesis of embryonic epithelium
epithelial cell differentiation
cell fate commitment
negative regulation of fat cell differentiation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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