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FIGURE: 1 / 4
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Positive Control: Mouse pancreas tissue lysate, rat pancreas tissue lysate, PC-3 cell lysates, rat pancreas tissue, human prostate tissue.
Subcellular Location: Cell membrane.
Rab proteins are low-molecular-weight GTP-binding proteins that form the largest branch of the Ras superfamily of GTPases. Located on the cytoplasmic face of organelles and vesicles, rab proteins are involved in intracellular membrane fusion reactions. Three membrane proteins, synaptosomal associated protein of 25 kDa (SNAP-25), synaptobrevin, and syntaxin, form the core of a ubiquitous membrane fusion machine that interacts with the soluble proteins N-ethylmaleimide-sensitive factor (NSF) and a-SNAP. Rab proteins, in coordination with the core fusion machinery and Munc-18, help to mediate vesicle docking and fusion. There exist over 40 rab proteins that have been described in mammals. Rab 3D has been shown to be present, in part, in the tongue, pancreas, and liver.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: epididymis secretory sperm binding protein; glioblastoma overexpressed; Rab3D upregulated with myeloid differentiation; ras-like low molecular mass GTP-binding protein; small GTPase; unnamed protein product
Gene Aliases: C130057E11Rik; D2-2; GOV; RAB16; RAD3D
UniProt ID: (Human) O95716, (Rat) Q63942, (Mouse) P35276
Entrez Gene ID: (Human) 9545, (Rat) 140665, (Mouse) 19340
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