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Invitrogen
Kir7.1 (KCNJ13) Polyclonal Antibody
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FIGURE: 1 / 2
Kir7.1 (KCNJ13) Antibody (PA5-119868) in IHC (P)
Immunohistochemistry (Paraffin) analysis of paraffin-embedded human small intestine tissue using Kir7.1 (KCNJ13) Polyclonal Antibody (Product # PA5-119868). The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0) for 20 minutes. The tissues were blocked in 1% BSA for 30 minutes at room temperature, washed with ddH2O and PBS, and then probed with the Kir7.1 (KCNJ13) a... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-119868
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein within C-terminal human KCNJ13/Kir7.1 from aa 200-aa360.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
TBS, pH 7.4, with 50% glycerol, 0.2% BSA
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Control: Rat brain tissue lysate, mouse brain tissue lysate, mouse cerebellum tissue lysate, human small intestine tissue.
Subcellular Location: Membrane.
Target Information
Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ13 has a very low single channel conductance, low sensitivity to block by external barium and cesium, and no dependence of its inward rectification properties on the internal blocking particle magnesium.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: inward rectifier K(+) channel Kir7.1; potassium channel, inwardly rectifying subfamily J member 13; potassium channel, inwardly rectifying subfamily J, member 13; potassium voltage-gated channel subfamily J member 13; unnamed protein product
Gene Aliases: KIR1.4; KIR7.1; LCA16; SVD
UniProt ID: (Human) O60928, (Mouse) P86046, (Rat) O70617
Entrez Gene ID: (Human) 3769, (Mouse) 100040591, (Rat) 94341
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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