Search
Invitrogen
ASCL3 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
FIGURE: 1 / 4
ASCL3 Antibody (PA5-142662) in IHC (P)
Immunohistochemistry analysis of ASCL3 in human brain, cortex. Samples were incubated with ASCL3 polyclonal antibody (Product # PA5-142662) using a dilution of 3.75 µg/mL. Formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-142662
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide with sequence C-HLPEDYLEKRLSK (aa 118-130).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Ammonium sulfate precipitation
Storage buffer
TBS, pH 7.3, with 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:8,000.
Target Information
ASCL3 is a protein coding gene, transcriptional repressor, and inhibits myogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: achaete-scute complex homolog 3; achaete-scute complex homolog-like 3; ASH-3; bHLH transcription factor Sgn-1 (Salivary Glands 1); bHLH transcriptional regulator Sgn-1; class A basic helix-loop-helix protein 42; ICRFP703B1614Q5.4; ICRFP703N2430Q5.4; mASH-3; mASH3
Gene Aliases: bHLHa42; HASH3; SGN1
UniProt ID: (Human) Q9NQ33, (Mouse) Q9JJR7
Entrez Gene ID: (Human) 56676, (Mouse) 56787
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
protein binding
protein dimerization activity
negative regulation of transcription from RNA polymerase II promoter
tissue homeostasis
regulation of transcription from RNA polymerase II promoter
salivary gland development
positive regulation of transcription from RNA polymerase II promoter
animal organ development
epithelium development
sensory epithelium regeneration
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support