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Invitrogen
TNNI1 Polyclonal Antibody
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FIGURE: 1 / 4
TNNI1 Antibody (PA5-145255) in WB
Western blot analysis of TNNI1 in various lysates. Samples were incubated with TNNI1 polyclonal antibody (Product # PA5-145255) using a dilution of 0.2 µg/mL followed by HRP-Linked Caprine Anti-Rabbit IgG secondary antibody at a dilution of 0.2 µg/mL. Lane 1: Rat Heart lysate; Lane 2: Rat Skeletal muscle lysate; Lane 3: Mouse Heart lysate; Lane 4: Mouse Skeletal muscle lysate.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-145255
Product Specifications
Species Reactivity
Human,
Mouse,
Pig,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Rat TNNI1 protein, Met1-Gln187 (Accession #P13413)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography, Protein A
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.05% Proclin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
Troponin proteins associate with tropomyosin and regulate the calcium sensitivity of the myofibril contractile apparatus of striated muscles. Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. The TnI-fast and TnI-slow genes are expressed in fast-twitch and slow-twitch skeletal muscle fibers, respectively, while the TnI-cardiac gene is expressed exclusively in cardiac muscle tissue. This gene encodes the Troponin-I-skeletal-slow-twitch protein. This gene is expressed in cardiac and skeletal muscle during early development but is restricted to slow-twitch skeletal muscle fibers in adults. The encoded protein prevents muscle contraction by inhibiting calcium-mediated conformational changes in actin-myosin complexes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: slow-twitch skeletal isoform; slow-twitch skeletal troponin I (TNN1); SSTNI; TNN1; TNNI1; troponin I; troponin I skeletal slow-twitch protein; troponin I type 1 (skeletal, slow); troponin I, skeletal, slow 1; unnamed protein product
Gene Aliases: 2700018B22Rik; SSTNI; TnI-S4; TNN1
UniProt ID: (Human) P19237, (Mouse) Q9WUZ5, (Rat) P13413
Entrez Gene ID: (Human) 7135, (Pig) 396947, (Mouse) 21952, (Rat) 29388
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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