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Invitrogen
ADAM9 Polyclonal Antibody
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FIGURE: 1 / 5
ADAM9 Antibody (PA5-17080) in ICC/IF
Immunofluorescence analysis of Disintegrin and metalloproteinase domain-containing protein 9 was performed using 70% confluent log phase A-431 cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 45 minutes at room temperature. The cells were labeled with ADAM9 Polyclonal Antibody (Product # PA5-17080) at 1:100 dilution in 0.1% BSA, incubated at 4 degree celsius overnight and then labeled with Donkey anti-Rabbit IgG (H+L) Highly Cross-Adsorbed... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-17080
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to the carboxy terminus of human ADAM9
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
44 µg/mL
Amount
4.4 µg
Purification
Antigen affinity chromatography, Protein A
Storage buffer
0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
ADAM9 is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This protein interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: a disintegrin and metallopeptidase domain 9 (meltrin gamma); a disintegrin and metalloproteinase; a disintegrin and metalloproteinase domain 9 (meltrin gamma); ADAM; ADAM metallopeptidase domain 9 (meltrin gamma); ADAMs; cellular disintegrin-related protein; cone rod dystrophy 9; MDC 9; meltrin gamma; metalloendopeptidases; metalloprotease/disintegrin/cysteine-rich protein 9; myeloma cell metalloproteinase; OTTHUMP00000216481; OTTHUMP00000216484; OTTHUMP00000216485; unnamed protein product
Gene Aliases: CORD9; MCMP; MDC9; mKIAA0021; Mltng
UniProt ID: (Human) Q13443, (Mouse) Q61072
Entrez Gene ID: (Human) 8754, (Rat) 290834, (Mouse) 11502
proteolysis
membrane protein ectodomain proteolysis
cell adhesion
cell-matrix adhesion
transforming growth factor beta receptor signaling pathway
response to manganese ion
cell migration
protein processing
keratinocyte differentiation
positive regulation of cell migration
membrane protein intracellular domain proteolysis
cell adhesion mediated by integrin
positive regulation of cell adhesion mediated by integrin
cell-cell adhesion mediated by integrin
positive regulation of macrophage fusion
response to tumor necrosis factor
response to laminar fluid shear stress
monocyte activation
response to hydrogen peroxide
amyloid precursor protein catabolic process
positive regulation of MAPK cascade
positive regulation of protein secretion
positive regulation of membrane protein ectodomain proteolysis
response to glucocorticoid
positive regulation of keratinocyte migration
response to calcium ion
cellular response to lipopolysaccharide
response to antineoplastic agent
integrin-mediated signaling pathway
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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