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Invitrogen
MST3 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-17285
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to residues of human Mst3
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Purification
Antigen affinity chromatography
Storage buffer
0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
STK24 (MST3) is a serine/threonine kinase that is a member of the GCK subfamily of STE20-like proteins. The yeast 'Sterile 20' gene (STE20) functions upstream of the mitogen-activated protein kinase (MAPK) cascade. In mammals, protein kinases related to STE20 can be divided into 2 subfamilies based on their structure and regulation. Members of the PAK subfamily (see PAK3; MIM 300142) contain a C-terminal catalytic domain and an N-terminal regulatory domain that has a CDC42 (MIM 116952)-binding domain. In contrast, members of the GCK subfamily (see MAP4K2; MIM 603166), also called the Sps1 subfamily, have an N-terminal catalytic domain and a C-terminal regulatory domain without a CDC42-binding domain. STK24 belongs to the GCK subfamily of STE20-like kinases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: epididymis secretory protein Li 95; mammalian STE20-like protein kinase 3; mammalian sterile twenty 3 kinase; OTTHUMP00000018594; protein kinase; protein serine/threonine kinase; RP11-111L24.5; serine/threonine kinase 24 (STE20 homolog, yeast); serine/threonine protein kinase; STE20-like kinase 3; STE20-like kinase MST3; sterile 20-like kinase 3; STK24; unnamed protein product
Gene Aliases: 1810013H02Rik; HEL-S-95; MST-3; MST3; MST3B; RGD1561742; STE20; STK3
UniProt ID: (Human) Q9Y6E0, (Rat) B0LT89, (Mouse) Q99KH8
Entrez Gene ID: (Human) 8428, (Rat) 361092, (Mouse) 223255
protein phosphorylation
intrinsic apoptotic signaling pathway in response to oxidative stress
cellular response to starvation
negative regulation of cell migration
cellular response to oxidative stress
intracellular signal transduction
protein autophosphorylation
regulation of axon regeneration
positive regulation of axon regeneration
execution phase of apoptosis
signal transduction
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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