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Invitrogen
HP1 gamma Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-17445
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to the amino terminus of human HP1gamma
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1.56 µg/mL
Amount
0.156 µg
Purification
Antigen affinity chromatography
Storage buffer
0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: chromobox homolog 3 (HP1 gamma homolog, Drosophila); hech; heterochromatin protein 1 gamma; heterochromatin protein 1 homolog gamma; heterochromatin protein HP1 gamma; heterochromatin-like protein 1; HGNC:1553; HP1 gamma; HP1 gamma homolog; HPy; modifier 2 protein; OTTHUMP00000202463; unnamed protein product
Gene Aliases: HECH; HP1-GAMMA; HP1g; HP1gamma; HP1Hs-gamma; M32
UniProt ID: (Human) Q13185
Entrez Gene ID: (Human) 11335, (Rat) 297093, (Mouse) 12417
transcription cofactor binding
chromatin binding
protein binding
enzyme binding
protein domain specific binding
identical protein binding
histone H3K9me2/3 reader activity
histone H1K26me1 reader activity
histone H1K26me2 reader activity
histone methyltransferase binding
transcription regulatory region sequence-specific DNA binding
DNA-binding transcription factor binding
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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