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Invitrogen
POU2F3 Polyclonal Antibody
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Product Details
PA5-19303
Product Specifications
Species Reactivity
Human
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide sequence (EPHLEASQHLPVPKH) corresponding to the internal amino acids of POU2F3 (aa 161-176).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Ammonium sulfate precipitation
Storage buffer
TBS, pH 7.3, with 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody is predicted to react with bovine, canine and rat based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.
Target Information
POU2F3 (POU class 2 homeobox 3) is a transcription factor that regulates gene expression by binding specific DNA sequences through its POU domain. It is best known for controlling the development and identity of tuft cells in epithelial tissues and has emerging roles in certain cancers, particularly tuft cell-like carcinomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Oct-11; Octamer-binding protein 11; Octamer-binding transcription factor 11; OTF-11; POU domain transcription factor OCT11a; POU domain, class 2, transcription factor 3; Skn-1a, Epoc-1; Transcription factor PLA-1; Transcription factor Skn-1; unnamed protein product
Gene Aliases: Epoc-1; OCT-11; OCT11; OTF-11; OTF11; PLA-1; PLA1; POU2F3; Skn-1a
UniProt ID: (Human) Q9UKI9
Entrez Gene ID: (Human) 25833
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
identical protein binding
sequence-specific DNA binding
sequence-specific double-stranded DNA binding
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
epidermis development
cell differentiation
keratinocyte differentiation
wound healing
negative regulation by host of viral transcription
positive regulation of transcription from RNA polymerase II promoter
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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