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Invitrogen
PSMB9 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-19384
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide sequence (RNISYKYRED) corresponding to the internal amino acids of PSMB9 (aa 104-113).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Ammonium sulfate precipitation
Storage buffer
TBS, pH 7.3, with 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody is predicted to react with bovine, canine, mouse, porcine and rabbit based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 2,000.
Target Information
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC in the immunoproteasome. Proteolytic processing is required to generate a mature subunit.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: class II MHC encoded; large multifunctional peptidase 2; large multifunctional protease 2; LMP-2; low molecular mass polypeptide 2; low molecular mass protein 2; macropain chain 7; MGC70470; multicatalytic endopeptidase complex chain 7; proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2); proteasome (prosome, macropain) subunit, beta type, 9; proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2); proteasome catalytic subunit 1i; proteasome chain 7; proteasome subunit beta 6i; proteasome subunit beta 9; proteasome subunit beta-1i; proteasome subunit beta1i; proteasome-related gene 2; proteosome (prosome, macropain) subunit, beta type 9; PSMB9; really interesting new gene 12 protein; RING12; RING12 protein; unnamed protein product
Gene Aliases: beta1i; LMP2; PRAAS3; PRAAS6; PSMB6i; RING12
UniProt ID: (Human) P28065, (Rat) P28077
Entrez Gene ID: (Human) 5698, (Rat) 24967
immune system process
proteasomal protein catabolic process
protein catabolic process
positive regulation of interferon-gamma production
positive regulation of interleukin-2 production
positive regulation of tumor necrosis factor production
response to interferon-gamma
proteasome-mediated ubiquitin-dependent protein catabolic process
CD8-positive, alpha-beta T cell differentiation
thymic T cell selection
T-helper 1 cell differentiation
negative regulation of regulatory T cell differentiation
T-helper 17 cell differentiation
CD8-positive, alpha-beta T cell homeostasis
liver development
response to xenobiotic stimulus
response to bacterium
muscle atrophy
antigen processing and presentation
response to alkaloid
spleen development
thymus development
cellular response to electrical stimulus
cellular response to interleukin-1
cellular response to virus
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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