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Invitrogen
GFR alpha-3 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-19875
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A peptide corresponding to amino acids from 347 to 360 of murine GFR alpha 3.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Ion-exchange chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
A suggested positive control is mouse heart tissue lysate.
PA5-19875 can be used with blocking peptide PEP-0010.
Target Information
GFRa-3 binds persephin, thus, persephin, GFRa-3, and Ret PTK form a complex to transduce persephin signal and to mediate persephin function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GDNF receptor alpha-3; GDNF receptor alpha-3 variant; GDNFR-alpha-3; GFR alpha-3; GFR-alpha-3; GFRalpha3; glial cell line derived neurotrophic factor family receptor alpha 3; glial cell line-derived neurotrophic factor receptor alpha-3; GPI-linked receptor; structurally related to members of the GFRa family of GPI linked receptors for glial cell line derived neurotrophic factor; GFRalpha-3; unnamed protein product
Gene Aliases: GDNFR3; GFRalpha3
UniProt ID: (Human) O60609, (Mouse) O35118
Entrez Gene ID: (Human) 2676, (Rat) 84422, (Mouse) 14587
neuron migration
transmembrane receptor protein tyrosine kinase signaling pathway
nervous system development
axon guidance
glial cell-derived neurotrophic factor receptor signaling pathway
sympathetic nervous system development
neuron development
signal transduction
peripheral nervous system development
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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