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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
A suggested positive control is rat brain tissue lysate.
PA5-20699 can be used with blocking peptide PEP-0814.
LRFN4 is one of a family of five transmembrane glycoproteins that are highly expressed in neuronal tissues. LRFN proteins share leucine-rich repeat (LRR)-immunoglobulin-like (Ig)-fibronectin type III (Fn)-transmembrane domain structure with other members of the LRR-Ig-Fn protein superfamily such as the Slitrk family of proteins. Expression of LRFN1, -3, and -4 mRNA was detected in embryonic neuronal cells, while Lrfn2 and Lrfn5 expression was primarily restricted to more mature cells. LRFN1, -2, and -4 bound to PDZ domains of postsynaptic PSD95, re-distributing PSD95 to the cell periphery. It has been suggested that the Lrfn proteins play a role in the developing and/or mature vertebrate nervous system. At least two isoforms of LRFN4 are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: fibronectin type III, immunoglobulin and leucine rich repeat domains 6; SALM3; synaptic adhesion-like molecule 3; unnamed protein product
Gene Aliases: FIGLER6; SALM3; SALM3.
UniProt ID: (Human) Q6PJG9, (Mouse) Q80XU8, (Rat) D4ABX8
Entrez Gene ID: (Human) 78999, (Mouse) 225875, (Rat) 688721
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