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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
A suggested positive control is THP-1 cell lysate.
PA5-20929 can be used with blocking peptide PEP-1043.
ZC3H12D, also known as MCPIP4, is a member of a family of novel CCCH-zinc finger proteins that includes ZC3H12A, a protein that is thought to be involved in macrophage activation, host immunity and inflammatory diseases. ZC3H12D is highly expressed in spleen, intestine, and colon. Similar to ZC3H12A and ZC3H12C, ZC3H12D expression in murine macrophages is also increased after treatment with lipopolysaccharide (LPS), although not to the same level as ZC3H12A. This pattern of expression was not duplicated in human-derived macrophages, suggesting it also may play a different role in host immunity and inflammatory response.
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Protein Aliases: RP1-281H8.5; transformed follicular lymphoma; tumor suppressor TFL; unnamed protein product; Zinc finger CCCH domain-containing protein 12D
Gene Aliases: C6orf95; dJ281H8.1; MCPIP4; p34; TFL
UniProt ID: (Human) A2A288
Entrez Gene ID: (Human) 340152
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