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Invitrogen
RASSF2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-21832
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human RASSF2. The exact sequence is proprietary.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.81 mg/mL
Amount
81 µg
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: H1299, Raji, mouse brain.
Predicted reactivity: Mouse (93%), Rat (94%), Chicken (82%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell cycle arrest. Stabilizes STK3/MST2 by protecting it from proteasomal degradation.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: centromere protein 34; KIAA0168; Ras association (RalGDS/AF-6) domain family 2; Ras association (RalGDS/AF-6) domain family member 2; RASSF2A; RASSF2B; RASSF2C; RP4-599I11.1; unnamed protein product
Gene Aliases: 3830431H01Rik; 9030412M04Rik; CENP-34; RASFADIN
UniProt ID: (Human) P50749, (Mouse) Q8BMS9
Entrez Gene ID: (Human) 9770, (Mouse) 215653
signal transduction
positive regulation of protein autophosphorylation
negative regulation of peptidyl-serine phosphorylation
positive regulation of apoptotic process
positive regulation of protein kinase activity
positive regulation of JNK cascade
protein stabilization
regulation of NIK/NF-kappaB signaling
skeletal system development
ossification
I-kappaB kinase/NF-kappaB signaling
regulation of osteoblast differentiation
regulation of osteoclast differentiation
bone remodeling
homeostasis of number of cells
negative regulation of NIK/NF-kappaB signaling
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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