HMGB1 Polyclonal Antibody, DyLight™ 650

four-way junction DNA binding bubble DNA binding transcription regulatory region sequence-specific DNA binding lipopolysaccharide binding phosphatidylserine binding DNA binding damaged DNA binding double-stranded DNA binding single-stranded DNA binding transcription coactivator activity transcription corepressor activity RNA binding double-stranded RNA binding single-stranded RNA binding cytokine activity integrin binding protein binding DNA binding, bending calcium-dependent protein kinase regulator activity lyase activity C-X-C chemokine binding protein kinase activator activity chemoattractant activity receptor agonist activity RAGE receptor binding RNA polymerase II sequence-specific DNA binding transcription factor binding DNA polymerase binding supercoiled DNA binding DNA-binding transcription factor binding endodeoxyribonuclease activator activity histone binding non-sequence-specific DNA binding, bending unmethylated CpG binding repressing transcription factor binding open form four-way junction DNA binding crossed form four-way junction DNA binding nucleic acid binding bent DNA binding 5S rRNA binding heparin binding peptide binding protein heterodimerization activity glycolipid binding

negative regulation of transcription from RNA polymerase II promoter cell morphogenesis eye development myeloid dendritic cell activation positive regulation of protein phosphorylation endothelial cell proliferation positive regulation of mesenchymal cell proliferation activation of innate immune response plasmacytoid dendritic cell activation macrophage activation involved in immune response inflammatory response to antigenic stimulus regulation of tolerance induction MyD88-dependent toll-like receptor signaling pathway regulation of T cell mediated immune response to tumor cell DNA repair base-excision repair double-strand break repair double-strand break repair via nonhomologous end joining chromatin organization nucleosome assembly chromatin remodeling chemotaxis inflammatory response immune response positive regulation of cytosolic calcium ion concentration nervous system development memory circadian rhythm negative regulation of DNA replication cell proliferation positive regulation of cell proliferation response to xenobiotic stimulus response to glucose positive regulation of autophagy positive regulation of neuron projection development positive regulation of smooth muscle cell migration negative regulation of RNA polymerase II transcriptional preinitiation complex assembly actin cytoskeleton organization lung development positive regulation of cell migration neuron projection development heterochromatin assembly DNA geometric change positive regulation of mismatch repair response to lipopolysaccharide negative regulation of interferon-gamma production positive regulation of chemokine production positive regulation of interferon-alpha production positive regulation of interferon-beta production positive regulation of interleukin-1 beta production positive regulation of interleukin-1 production positive regulation of interleukin-10 production positive regulation of interleukin-12 production positive regulation of interleukin-6 production positive regulation of interleukin-8 production positive regulation of tumor necrosis factor production response to insulin positive regulation of myeloid cell apoptotic process V(D)J recombination toll-like receptor 2 signaling pathway positive regulation of toll-like receptor 2 signaling pathway toll-like receptor 4 signaling pathway positive regulation of toll-like receptor 4 signaling pathway positive regulation of toll-like receptor 9 signaling pathway response to interferon-gamma T-helper 1 cell activation endothelial cell chemotaxis psychomotor behavior positive regulation of activated T cell proliferation positive regulation of apoptotic process apoptotic cell clearance negative regulation of CD4-positive, alpha-beta T cell differentiation positive regulation of MAPK cascade positive regulation of blood vessel endothelial cell migration negative regulation of blood vessel endothelial cell migration T-helper 1 cell differentiation positive regulation of innate immune response response to ethanol positive regulation of cell differentiation positive regulation of myeloid cell differentiation positive regulation of myoblast differentiation positive regulation of glycogen catabolic process positive regulation of mitotic cell cycle positive regulation of transcription from RNA polymerase II promoter positive regulation of JNK cascade response to antibiotic male-specific defense response to bacterium induction of positive chemotaxis regulation of DNA metabolic process response to glucocorticoid neuron apoptotic process myoblast proliferation protein-containing complex assembly positive regulation of ERK1 and ERK2 cascade cellular response to lipopolysaccharide cellular response to cytokine stimulus cellular response to interleukin-1 positive regulation of monocyte chemotactic protein-1 production positive regulation of macrophage inflammatory protein 1 alpha production positive regulation of monocyte chemotaxis positive regulation of wound healing neutrophil clearance cellular response to interleukin-7 positive regulation of NIK/NF-kappaB signaling positive regulation of sprouting angiogenesis positive regulation of vascular endothelial cell proliferation positive regulation of chemokine (C-X-C motif) ligand 2 production negative regulation of apoptotic cell clearance regulation of nucleotide-excision repair positive regulation of dendritic cell differentiation positive regulation of endothelial cell proliferation dendritic cell chemotaxis DNA metabolic process DNA topological change DNA recombination signal transduction negative regulation of endothelial cell migration positive regulation of DNA binding positive regulation of viral entry into host cell regulation of viral process positive chemotaxis regulation of hemopoiesis adaptive immune response B cell proliferation involved in immune response regulation of transcription from RNA polymerase II promoter autophagy activation of protein kinase activity toll-like receptor 9 signaling pathway innate immune response DNA ligation involved in DNA repair positive regulation of DNA ligation tumor necrosis factor secretion chromatin silencing regulation of restriction endodeoxyribonuclease activity positive regulation of cysteine-type endopeptidase activity involved in apoptotic process