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Invitrogen
SNX27 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-23025
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide made to an internal portion of human SNX27 (within residues 450-500).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS with 30% glycerol
Contains
0.1% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody is predicted to react with rat, bovine and zebrafish based on 100% sequence homology.
Target Information
SNX27 encodes a member of the sorting nexin family, a diverse group of cytoplasmic and membrane-associated proteins involved in endocytosis of plasma membrane receptors and protein trafficking through these compartments. All members of this protein family contain a phosphoinositide binding domain (PX domain). A highly similar protein in mouse is responsible for the specific recruitment of an isoform of serotonin 5-hydroxytryptamine 4 receptor into early endosomes, suggesting the analogous role for the human protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: KIAA0488; MAP-responsive gene protein; methamphetamine (MAP) responsive transcript 1; methamphetamine-responsive transcript 1; methamphetamine-responsive transcript 1 protein; PDZ-protein Mrt1; RP11-98D18.12-005; sorting nexin family member 27; unnamed protein product
Gene Aliases: 5730552M22Rik; DADAND; ESTM45; ESTM47; MRT1; MY014
UniProt ID: (Human) Q96L92, (Mouse) Q3UHD6, (Rat) Q8K4V4
Entrez Gene ID: (Human) 81609, (Mouse) 76742, (Rat) 260323
intracellular protein transport
signal transduction
endosome to lysosome transport
endosomal transport
endocytic recycling
establishment of protein localization to plasma membrane
regulation of synapse maturation
neurotransmitter receptor transport to plasma membrane
regulation of postsynaptic membrane neurotransmitter receptor levels
endosome to plasma membrane protein transport
negative regulation of inward rectifier potassium channel activity
positive regulation of AMPA glutamate receptor clustering
establishment of natural killer cell polarity
nervous system development
response to methamphetamine hydrochloride
cellular response to nerve growth factor stimulus
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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