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Invitrogen
HMGB3 Polyclonal Antibody
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FIGURE: 1 / 1
HMGB3 Antibody (PA5-23362) in WB
Western blot analysis of HMGB3 in mouse placenta lysate in the 1) absence and 2) presence of immunizing peptide. Samples were incubated in HMGB3 polyclonal antibody (Product # PA5-23362) using a dilution of 0.5 µg/mL followed by a goat anti-rabbit Ig HRP secondary antibody. PicoTect ECL substrate solution was used for this test.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-23362
Product Specifications
Species Reactivity
Bovine,
Dog,
Chicken,
Horse,
Human,
Mouse,
Non-human primate
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A portion of amino acids 150-200 of human HMGB3.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS with 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
HMGB3 belongs to the high mobility group protein superfamily. Like HMG1 and HMG2, HMGB3 contains DNA-binding HMG box domains and is classified into the HMG box subfamily. Members of the HMG box subfamily are thought to play a fundamental role in DNA replication, nucleosome assembly and transcription.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: high mobility group protein 1; high mobility group protein 2a; high mobility group protein 4; high mobility group protein B1; high mobilty group protein 2A; high-mobility group (nonhistone chromosomal) protein 4; HMG-2a; HMG-4; HMGB3 transcript variant 1/2; MGC90319; similar to high mobility group 1 and 2 proteins; unnamed protein product
Gene Aliases: HMG-1; HMG-2a; HMG-4; HMG2A; HMG4; HMGB1
UniProt ID: (Chicken) P40618, (Human) O15347, (Bovine) Q32L31, (Mouse) O54879
Entrez Gene ID: (Chicken) 396232, (Horse) 100069284, (Human) 3149, (Dog) 481073, (Bovine) 613729, (Mouse) 15354
DNA geometric change
negative regulation of B cell differentiation
negative regulation of myeloid cell differentiation
DNA recombination
chromatin remodeling
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
innate immune response
positive regulation of innate immune response
positive regulation of transcription from RNA polymerase II promoter
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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